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However, research shows that high-dose vitamin K supplements can interact with common blood-thinning medications like warfarin (Coumadin). These medications work by blocking vitamin K’s effects to prevent dangerous clots. Suddenly adding extra vitamin K through pills can reduce how well the medication works, potentially allowing clots to form more easily. Studies, including those from the American Heart Association, note that inconsistent or excessive vitamin K intake may shift this delicate balance, raising worries about vascular events in older adults already managing heart rhythm issues or prior clot risks.